A novel approach to medical countermeasures against organophosphorus compound toxicity

Organophosphorus Compound Induced 'Intermediate Syndrome'

Zebrafish screen identifies novel compound with selective toxicity against leukemia.

To detect targeted antileukemia agents we have designed a novel, high-content in vivo screen using genetically engineered, T-cell reporting zebrafish. We exploited the developmental similarities between normal and malignant T lymphoblasts to screen a small molecule library for activity against immature T cells with a simple visual readout in zebrafish larvae. After screening 26 400 molecules, w...

A Study on Countermeasures against Steganography: an Active Warden Approach

Digital steganography is a method used for hiding information in digital images. It can be used for secure communication. There have been many robust digital steganography methods invented in recent decades. The steganographic message can be inserted in multimedia cover signal such as audio, image and video. However, this technique also may be used by malicious users to transmit dangerous infor...

Therapeutic effects of HESA-A (a herbal-marine compound) in acute organophosphorus pesticide poisoning

Objective: Organophosphorus compounds (OPs) are common causes of poisonings. Atropine and oximes are pharmacological antidotes of OPs. However, because of their adverse effects and insufficient performance, several other compounds have been evaluated as adjuvant therapy. HESA-A is a herbal-marine drug that contains material from Carum carvi (Persian cumin), Penaeus latisculatus...

A novel approach to medical image compression

As medical/biological imaging facilities move towards complete film-less imaging, compression plays a key role. Although lossy compression techniques yield high compression rates, the medical community has been reluctant to adopt these methods, largely for legal reasons, and has instead relied on lossless compression techniques that yield low compression rates. The true goal is to maximise comp...